BCR-ABL
Chronic myelogenous leukemia (CML)
Acute lymphoblastic leukemia (ALL)
bcl-2
Follicular and undifferentiated lymphomas
BRAF
Melanoma, Hairy Cell Lymphoma
c-myc
Burkitt lymphoma
HER2/neu (c-erbB2)
breast
ovarian
gastric carcinomas
L-myc
Lung tumor
N-myc
Neuroblastoma
ras
colon cancer
lung cancer
pancreatic cancer
most common point mutation causing CA
ret
MEN 2A & 2B
(multiple endocrine neoplasia)
APC
colorectal cancer (associated with FAP)
DCC
Colon cancer
BRCA 1 & 2
Breast cancer
ovarian cancer
p53
Li-Fraumeni syndrome
most human cancers
Rb
Retinoblastoma
osteosarcoma
WT1 & 2
Wilms Tumor
VHL
von Hippel-Lindau disease
p16
Melanoma
CEA
4 adenocarcinoma's
1. colonic
2. pancreatic
3. breast
4. gastric
PDGF
Astrocytoma
Follicular B Cell
t(14;18)
CD19, CD20, CD10
Diffuse Large B cell
CD20
SLL or CLL
B cell: CD19, CD20,
T cell: cd23, CD43, CD5
Burkitt Lymphoma
t(8;14)
t(2;8) , t (8;22)
Hairy Cell lymphoma
CD11, CD20, CD25, CD103
Dry Tap
Hair cell lymphoma
Aplastic Anemia
Primary Myelofibrosis
Range of Plasma cell Neoplasms
Multiple myeloma - IgG
Waldenstrom Macroglobulinemia - IgM
Hodgkin's
Classical: CD15, CD30
Variant: CD20, CD45