Pharmacokinetics
The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. ADME
pharmacology
the study of drugs and their interactions with living systems
Prodrugs
drugs that are inactive until metabolized into an active form
Pharmacodynamics
The study of what the drug does to the body
Toxicology
The study of poisons, including toxic drug effects, and applicable treatments.
Goal Drug
produces desired effect, minimal dosage and frequency, optimal onset and duration of activity, no side effects, X
Mechanism-based drug design
involves molecular modification in designing a drug that interferes specifically with the known or suspected biochemical pathway or mechanism of a disease process
Lead compound
a prototype chemical compound
Treatment IND
submitted for experimental drugs showing promise in clinical testing for serious or immediately life-threatening conditions while the final clinical work is conducted
Random Screening
testing large numbers
Molecular Modification
a chemical alteration of a known and previously characterized organic compound for the purpose of enhancing its usefulness as a drug
Drug Price Competition and Patent Term Restoration Act of 1984
it is already allowed to produce the samedrug and market it (5 days prior to theexpiry of the patent term).
Dietary Supplement Health and Education Act of 1994
This act changed the definition and regulations for dietary supplements