PD/LMNL

B (small lung cancer)

1. The NMJ disease most commonly seen in maleassociated with pulmonary cancerA. Myasthenia GravisB. LEMSC. BotulismD. ALS

C

2. Most common spinal segment affected by poliovirusgroup?A. CervicalB. ThoracicC. LumbarD. Sacral

A

3. It is known as auto immune disease of peripheralnervous system?A. GBSB. ALSC. SMAD. CMTD

B

4. A GBS variant which has a symptoms such asopthalmoplegia, ataxia & areflexiaA. Mary walker variantB. Miller fisher variantC. Marburgs variantD. Morquios variant

A

5. Which of the following is not a criterion in post-poliosyndromeA. confirmed history of non-paralytic poliomyelitisB. a period of partial to complete functional andneurologic recoveryC. no other medical explanation for this conditionD. onset of new muscle weakness

E

6. These are signs and symptoms of asymptomaticpoliomyelitis, Except:A. sensory lossB. weaknessC. muscle sorenessD. autonomic dysfunctionE. AOTA

B

7. Which of the following is not seen in amyotrophiclateral sclerosisA. babinski and hoffman reflexesB. severe cognitive deteriorationC. spasticityD. head dropE. cadaveric hand

D

8. Juvenile SMA is known as:A. werdnig hoffmanB. Type II muscular atrophyC. chronic werdnig hoffmanD. kugelberg welander SMAE. AOTA

A

9. Motor Neuron Dse secondary to infection fromclostridium butolinumA. BotulismB. BotulinismC. GBSD. LEMS

E

10. True about LEMS:A. Decrementing responseB. Distal muscle weaknessC. OphthalmoplegiaD. ThymomaE. NOTA

D

11. It is the mechanism of action of auto antibodies in MGA. Acetylcholine breakdownB. Acetylcholine vesicle breakdownC. Acetylcholinesterase breakdownD. Acetylcholine receptor breakdown

E

12. Pathology of what organ in the body is associatedwith LEMSA. ThymusB. ThyroidC. HeartD. LiverE. Lungs

B

13. Which of the following has viral etiology?A. ParkinsonismB. Guillan Barre SyndromeC. TBID. Multiple sclerosis

C

14. A patient reports weakness and tingling in the lowerextremities over the past 2 weeks. The therapistsuspects that the patient may have GBS. Which of thefollowing examination findings would most likelyoccur with this diagnosis?A. Hypertonicity in the affected muscleB. Presence of the clonus with rapid passive footdorsiflexionC. Diminished tendon reflexesD. Ataxic gait pattern

B

15. You are presenting an inservice about diseases of the muscle at a local community center. Which of thefollowing muscle diseases has abnormal fatiguabilityof muscle as one of its main symptom?A. Myotonia congenitaB. Myasthenia gravisC. Guillan Barre syndromeD. Muscular dystrophy

B

16. A patient informs his therapist that his problem began 3 months after a bout of the flu. The patient originally experienced tingling of the hands and feet. He also reports progressive weakness to the point that he required ventilator to breathe. He is now recoveringrapidly and is expected to return to a normal functionlevel in 3 months. From which of the followingcondition is the patient most likely suffering?A. Parkinson's diseaseB. Guillan Barre syndromeC. Multiple sclerosisD. Amyotrophic lateral sclerosis

B

17. A 15-year-old with kugelberg welander disease willexhibit all of the following manifestations, EXCEPT:A. Gower's signB. Hyperactive DTRsC. Minimal ambulation capabilityD. Muscle weakness

D

18. Included in the manifestation of GBS?A. Hyper reflexiaB. Descending paralysisC. Slow progressionD. Facial palsyE. None of these

E

19. Disorder of the neuromuscular junctionA. Myasthenia gravisB. Myasthenic syndromeC. BotulismD. A and BE. AOTA

D

20. Juvenile SMA is known as:A. Wednig HoffmanB. Type II muscular atrophyC. Chronic wednig HoffmanD. Kugelberg welander SMAE. AOTA

C

21. Primary drug for Amyotrophic lateral sclerosisA. TrihexyphenidylB. GuanidineC. RiluzoleD. Sinemet

B

22. All of the following are true statements about SMA II, EXCEPTA. Also known as the chronic infantile SMAB. The usual onset is before 6 monthsC. Pt is able to sit independentlyD. Severe progressive scoliosis is a commonsymptom for this conditionE. None of these

D

23. In this condition, there is a mutation of androgenreceptor gene that causes degeneration of LMNsleading to weakness and atrophy of bulbar, facial, andlimb muscles. Endocrinologic disturbances, sensoryimpairment, proximal or distal weakness are commonfindings for this condition.A. Acute werdnig Hoffman diseaseB. Chronic werdnig Hoffman diseaseC. Kugelberg wellanderD. Kennedy's diseaseE. None of the above

A

24. Most common viral strain of poliovirus?A. BrunhildeB. LansingC. LeonD. None of these

B

25. Most common variant of GBSA. Miller fisher syndromeB. Acute inflammatory demyelinatingpolyneuropathyC. Acute motor axonal neuropathyD. Acute motor sensory axonal neuropathy

D

26. A patient in the late stages of Parkinson's diseaseexhibits episodes of akinesia while walking. Whatshould the therapist examine?A. Primary involvement of the head and trunkB. Associated dyskinesiasC. Primary involvement of the hips and kneesD. Triggers that precipitate the freezing episodes.

C

27. A patient with a 7-year history of Parkinson's diseaseis hospitalized. The patient is ambulatory but requiresclose supervision to prevent falls. What should be thefocus of the physical therapist's plan of care?A. Manual balance perturbation trainingB. Transfer and wheelchair trainingC. Caregiver training for contact guarding duringlevel walking and stairsD. Locomotor training using a rolling walker

C (rhythmin initiation to help with respiratory issues)

28. A patient with a 6-year history of Parkinson's disease(PD) has experienced two recent bouts of pneumoniaand limited functional mobility in the home. Thetherapist's plan of care focuses on improvingrespiratory function and postural control. What is theBEST choice for intervention to address these issuesat this time?A. Supine, UE PNF lift and reverse lift patterns usingrhythmic initiationB. Quadruped, alternate arm and leg raisesC. Sitting, bilateral symmetrical UE PNF D2 flexionpatterns using rhythmic initiationD. Standing, bilateral symmetrical UE PNF D2 flexionpatterns using dynamic reversals

C

29. A PTA is assigned to ambulate a patient with a 10-yearhistory of Parkinson's disease (PD). What should thePT instruct the PTA to watch for?A. Wider steps and increased double support timeB. An abnormally wide base of supportC. Decreased trunk rotation with shorter stepsD. Unsteady, uneven gait with veering to one side

C

30. Triad of huntington disease, EXCEPT:A. DementiaB. ChoreaC. DystoniaD. Depression

D (tremor + rigidity)

31. The patient is complaining of heaviness and stiffnessof his limbs which is felt uniformly in both agonist andantagonist muscles and in movements in bothdirection. It is also noted that it occurs with tremors.As a PT/OT, you suspect that the patient may have?A. RigidityB. BradykinesiaC. TremorD. Cogwheel rigidityE. Plastic rigidity

E (disappears at sleep)

32. All of the following are true about the tremor seen inPD patient, EXCEPT:A. Described as involuntary shaking or oscillatingmovement of a part of parts of body resultingfrom contraction of opposing musclesB. It can occur in jaw or tongueC. Present at rest, suppressed briefly by voluntarymovementD. None of theseE. It appears with sleep

A (although resting tremor is the more specific answer, Sullivan only states tremor)

33. Most common presenting symptom of PD?A. TremorB. BradykinesiaC. Unilateral rigidityD. Resting tremorE. Postural instability

C

34. Most common cause of toxic parkinsonism:A. Wilson diseaseB. None of theseC. ManganeseD. Hepatocerebral degeneration

C

35. Impaired righting reflexA. IB. IIC. IIID. IVE. V

D

36. Secondary PD, EXCEPT:A. Wilson's diseaseB. Toxic PDC. Encephalitis lethargicaD. Multisystem atrophyE. Hepatocerebral degeneration

A

37. Gold Standard Drug Therapy for PDA. L-dopaB. PramipexoleC. TrihexyphenidylD. Selegiline

B (Should be PARK 1)

38. All of the following are genes involved in familial PD,EXCEPT:A. PINK 1B. PARK 2C. LRRK 2D. DJ-1E. None of these

A

39. Sustained contraction of agonist and antagonistmuscleA. DystoniaB. ParatoniaC. ChoreaD. Hemiballismus

C

40. Most common type of PDA. Familial PDB. Secondary PDC. Sporadic PDD. Early-onset PD

C

41. A diagnostic test for PDA. SinemetB. Tensilon testC. Apomorphine testD. Levodopa

A

42. The speech disturbance in parkinson's patients isdescribed as:A. Hypokinetic dysarthriaB. Hyperactive dysphasiaC. MutismD. HypomemiaE. None of these

C (bradykinesia)

43. Most disabling problem in PD is:A. BradyphreniaB. Early fatigueC. Slowness of movementD. Postural instability

C (should be dopaminergic)

44. The following statements describe Parkinson'sdisease, EXCEPT:A. None of theseB. Bradykinesia and rigidity are characteristics ofthe diseaseC. It is due to the degeneration of the cholinergicneuronsD. Its clinical manifestations include tremorsE. It cannot be completely reversed by givinglevodopa

B

45. Cardinal signs of PD, except:A. Resting tremorB. BradyphreniaC. Postural InstabilityD. RigidityE. None of these

C

46. All of the following are true about chronic-werdnigHoffman disease except:A. Slowly progressiveB. Onset 6-12 monthsC. Autosomal dominantD. Chromosome 5q abnormality

A (AT LEAST 3/4 UMN and LMN signs)

47. El Escorial criteria for clinically definite ALS:A. UMN, LMN signs in 4 region of the bodyB. UMN, LMN signs in 2 region of the bodyC. LMN signs in 1 region of the bodyD. UMN in 2 regions of the bodyE. None of these

B

48. Patients have mutation in the gene encoding copperzinc superoxide dismutase (SOD1)A. Juvenile ALSB. Familial ALSC. SporadicD. ALSALS-PD-FTD complex

B

49. You are treating a patient with Amyotrophic LateralSclerosis. The least likely manifestation that you see is:A. (+) clonusB. Limitation of gazeC. WeaknessD. Increase muscle tone

A (PRE-SYNAPTIC = LEMS, BOTULISM!! destruction of vesicles for ACH = LEMS)

50. IgG blocks the presynaptic vesicles leading to adecrease or defective release of Acetylcholine. On ESmm function will improve or has an incremental effect.A. Eaton-Lambert DiseaseB. ThymomaC. Myasthenia Gravis form1D. Myasthenia Gravis form2E. Myasthenia gravis form 3