Pathology 140, Endocrine and infectious disease

Hepatitis A (acute)

Direct contact or by fecal-contaminated food or water

Hepatitis B virus

virus that causes inflammation of the liver; transmitted through any body fluid, including vaginal secretions, semen, and blood

Hepatitis C virus

Intravenous drug use, Not sterilised medical

Hepatitis D virus

Spread through contact with infected blood

Hepatitis E virus

Blood to blood contact unsafe sex and during childbirth

HIV

Immunodeficiency virus that attacks and destroys the human immune system. Prevention: pharmaceutical therapy.

AIDS (acquired immune deficiency syndrome)

Failure of the body to develop antibody to infecting organism. it caused dementia complex, pneumonia.

Sexually Transmitted Diseases ( STDs )

Gonorrhoea, Chancroid, Human papillomavirus, Chlamydia, Syphilis ,Cytomegalovirus CMV )

nosocomial infection

an infection acquired during hospitalization, Three groups, patient related,organisation,latrogenic

Dengue fever and Dengue hemorrhagic fever

Attacked platelet, Virus, Mosquito, Aedes aegypti

Hantaviruses

RNA viruses, Rodents, Causes hemorrhagic fever

Malaria

Yellow skin ,Attacks the liver

Plague

Rodents,domestic cats and dogs , sheep and camels

Rabies

saliva of an infected animal

Rocky Mountain spotted fever

Bacteria Rickettsia ricketsii,Ticks

Typhus

Bacteria from Rickettsia genus transmitted by fleas and lice,Epidemic typhus is more serious. Rickettsia prowazekii and Endemic and murine.

West Nile Encephalitis

inflammation of the brain caused by West Nile Virus.Eye pain

Yellow Fever

a disease transmitted by mosquitoes.Three types, sylvatic(jungle)Intermediate, urban.

Diphtheria

an acute disease caused by Corynebacterium diphtheriae, fever, painful swallowing and changes of skin color,hypoxia.

Mumps

swelling in neck( parotitis), in children, male on testies, paramyxovirus

whooping cough

pertussis, first stage is thick mucus.second stage is whooping noise, third stage recovery.

poliomyelitis (polio)

inflammation of the gray matter of the spinal cord, transmitted orally, unilateral leg.

Rubella (German Measles)

reddish pink rash; RNA morbillivirus, fever

Tetanus

lockjaw

Varicella Zoster Virus

chicken pox in children, shingles in adults.

Legionellosis / Legionnaires ' disease

known as Pontiac fever Bacteria Legionella with high fever Simmilar to Pneumonia but Pneumonia low Fever.

Variola

smallpox, monkey pox, pus filled spot. Vomiting, hemorrhage. spread by fluid.

Meningitis

lining Brian an spinal cord.Involuntary eye-movement , fever , stiffness of the neck, seizures.

toxic shock syndrome

Bacteria Can send body To Shock, found in blood storm.

chain of infection

Pathogens, susceptible host, Port of entry, reservoir, port of exit, mode of transmission-infectious.

Pituitary hypofunction

Simmonds disease, Diabetes insipidus,Sheehan's syndrome,Pituitary dwarfism.

Simmonds disease

Hypofunction of the anterior pituitary (panhypopituitarism),

diabetes insipidus

Damage to the posterior pituitary gland reduce production of anti-diuretic hormone.

Sheehan syndrome

Blood loss to the pituitary during pregnancy

pituitary dwarfism

lack of growth hormone, normal proportions with short stature, Without loss to pituitary during pregnancy

hyperpituitarism

the excess secretion of growth hormone that causes acromegaly and gigantism

Acromegaly

enlargement of the extremities, Cause hyperglycemia

Gigantism

abnormal growth of the entire body that is caused by excessive secretion of growth hormone before puberty

Thyroid disease

disorders resulting from defects of the thyroid gland, can be genetic or acquired, results in either an increase or decrease in metabolism, controlled by drugs or surgery

Hyperthyroidism

excessive activity of the thyroid gland, T3 and T4. Can calls mood swing tachycardia congestive heart failure double vision nervousness tremor.

Graves' disease

Bulging eye

Goiter

enlargement of the thyroid gland, horizontal swelling on the interior of the neck. hyperplasia of the thyroid,tumor mostly benign,iodine salt.

Hypothyroidism

A disorder caused by a thyroid gland that is slower and less productive than normal

certinism

Congenital hypothyroidism

Hashimoto Disease (thyroiditis)

autoimmune disease of the thyroid gland, scar, fibrous tissue, shrinking of thyroid.

Congenital aplasia

lack of thyroid gland at birth

secondary hypothyroidism

caused by pituitary disease

tertiary hypothyroidism

defect in hypothalamus

Parathyroid disease

low calcium

hyperparathyroidism

excessive production of parathyroid hormone (PTH)

Primary hyperparathyroidism

Adenomas, hyperplasia, carcinoma, Over secretion of phosphate from kidney

Secondary hyperparathyroidism

Low levels of calcium, vitamin D deficiency

Tertiary hyperparathyroidism

Ran calcium level in the urine raise shortly

hyperparathyroidism pt intervention

Care must be taken when working with people with hyper parathyroidism because there is an increased danger of fracture as a result of the osteoporosis they getting fatigue Quickly

Hypo-parathyroidism

Causes hypocalcemiaLow level of calcium, loss of PTH hormone ,Can cause cramps and Convulsions, spasm in brain.

Adrenal Cortex Diseases

Addison's Disease ,Adrenocortical Hypofunction, Hypocortisolism, Adrenal Insufficiency.

Adrenal Insufficiency (Addison's Disease)

adrenal cortex does not produce enough hormone (cortisol or aldosterone)acute or chronic

adrenal insufficiency

May be either a primary such as a Addison disease or secondary from external factors.

primary disease

Resulting from a defect within the structure and not caused by an external factor.

Primary adrenocortical insufficiency

Autoimmune distraction of a adrenal gland.polyendocrine deficiency syndrome.

Addison Disease

Decrease cortisol and aldosterone. cortisol is particular to controlled blood pressure and cardiovascular function inhibits the inflammatory response and assist control of insulin and regulation of protein and metabolism.

Cushing syndrome

group of signs and symptoms produced by excess cortisol from the adrenal cortex, pituitary gland type two diabetes.

Cushing's syndrome

Obesity,moon face, hirsutism (excessive hair growth),impaired immune system,myopathy.

buffalo hump

Cushing's

Conn's syndrome

a disorder of the adrenal glands due to excessive production of aldosterone, cortex, kidney, hypokalemia, Low level of potassium

Adrenal medulla disease

Pheochromocytoma and neuroblastoma

Neuroblastoma

malignant tumor, grow rapidly, mainly in children.

Pheochromocytoma

tumor of the adrenal medulla, Lost tomorrow in adult usually benign.

diabetes mellitus

Chronic metabolic disorder lack of insulin produce by pancreas.

Type one diabetes

Diabetes which is caused when the pancreas cannot make insulin. The body destroy its own pancreatic. Insulin dependent most in children hypoglycemia.

type 2 diabetes

Diabetes of a form that develops especially in adults and most often obese. Insulin resistance, more gradually. Non-insulin dependent the body either does not produce sufficient in soline or the body is unable to utilize what is produce. hyperglycemia.

Diabetic neuropathy

too much blood sugar can make neurons less/more sensitive to pain. No blood flow, usually peripheral ,lower extremity, delay wound Hilling.

diabetic coma

caused by very high blood sugar (hyperglycemia), Results by infection

Normal range of blood sugar

Fasting blood sugar, 80-120 mg, hypoglycemia 70 mg, hyperglycemia 150 mg, after two hours of eating.

Hypoglycemia

Too much insulin, Can occur precipitously, neuron symptoms, ataxia, increase Pauls,

ketoacidosis

Too little insulin, develop slowly, dehydration, dry skin, low blood pressure , acidic symptoms ,vomiting .

Metabolic disorders

PhenylketonuriaWilson's disease

Phenylketonuria

Autosomal, abnormalities of white matter, seizure, differential diagnoses, testing dementia.

Wilson's disease

Incurable but can be control. differential diagnoses of liver disease or heart failure, vomiting blood.

eating disorders

Obesity, anorexia nervosa ( body image) ,bulimia nervosa( self vomiting) , vitamin deficiency( poor reduction absorption) metabolic disorders.

Mineral Deficiencies

calcium, magnesium, zinc, iron, chloride, iodine.

Body type; shape

Ectomorph small frame, mesomorph,medium, endomorph, fat.