MURI session 4 : Urine formation 1

list the nine functions of the kidneys

• Regulation of body fluid osmolality and electrolyte concentrations• Regulation of arterial blood pressure• Regulation of acid-base balance• Regulation of erythrocyte production• Regulation of 1, 25-dihydroxy vitamin D3 (Calcitriol) production• Synthesize glucose from AA's (Gluconeogenesis)• Production of hormones/-like substances (Somatomidin and prostaglandins)• Excretion of metabolic waste products and foreign chemicals

Processes of urine formation

filtrationreabsorptionsecretionexcretion

Glomerular Filtration Rate

125 ml/min

Reabsorption rate (back into circulation )

124 ml/min

Urinary excretion rate

1 mL/min

How does the kidney handle creatinine ?

filtered only rate of filtration = rate of excretion 100% found in urine

How does the kidney handle electrolytes ?

filtered partially reabsorbed

How does the kidney handle glucose ?

filtered and completely reabsorbed

How does the kidney handle acid and bases ?

filtered and excreted