Clopidogrel (plavix)

Anti-platelet aggregate

Indications

AMI, CVA, ACS, peripheal artery disease

MOA

Inhibits binding of adenosine diphosphate to its platelet receptor, preventing platelet aggregation; thus preventing clots

Contraindications

GI/ intracranial bleeding

Side effects

Increased bleeding, diarrhea

Adult dose

75mg/ day PO, 300mg loading dose for N-stemi AMI's

Pedi dose

0.2-1 mg/kg/day

Determine the oxidation number of P in P₂O₅. +5 +3 -2 +2