Atrial Fibrillation with Rapid Ventricular Rate

If afib with RVR tell who

Attending must be notified via text page at this point

In acute stroke patients what should you consider

Strongly consider digoxin over amiodarone

What is considered afib with RVR in this algorithm

Irregularly irregular rate and rhythm with ventricular rate >110

While assessing hemodynamics

MgSO4 IV 2 g (?)

If unstable

SBP <90 over 30 minutes or on inotropic agent,ACLS/cardioversion

If marginally stable

SBP 90-120, recent stroke, evidence of perfusion-dependence

What do you do for marginally stable

Continuous infusion for ventricular rate control of ESMOLOL 10 mg bolus and drip at 50 mcg/kg/min

How do you titrate esmolol for this purpose

Titrate in 50 mcg/kg/min increments q 5 minutes to maximum dose of 200 mcg/kg/min

If goal HR is not achieved with esmolol for moderately stable,

Start eitherAmiodarone IV 150 mg bolus +/- drip at 1 mg/min x 72 hours. Repeat bolus as tolerated to achieve rate controlORDigoxin IV 5 mcg/kg load, then 2.5 mcg/kg q 6 hour 2xStrongly consider cardiology consultation

If patient is stable they are

SBP >120, on no inotropic agents, recent stroke or evidence of perfusion-dependence

If stable, do what first

Metoprolol IV 5 mg 1 5 minutes up to 3 doses as tolerated

If metoprolol works, do what next

Start metoprolol IV 5 mg q 6 hours

If metoprolol doesn't work

Continuous infusion for ventricular rate control using:1st line or 2nd line drugs

1st line for continuous infusion for ventricular rate control

Esmolol 10 mg bolus and drip at 50mcg/kg/min. Titrate in 50 mcg/kg/min increments q 5 minutes to maximum dose of 200 mcg/kg/min

2nd line for continuous infusion for ventricular rate control in STABLE patient

If goal HR not achieved, STOP esmolol, start diltiazem IV .25 mg/kg, can repeat once at 5 minutes. Start diltiazem drip at 5-15 mg/hr

If therapy is effective in stable patient with 1st or 2nd line ventricular rate control or marginally stable in pt with amiodaronge or digoxin...

START long-acting therapy at 6 hours

If 1st line and 2nd line treatment for stable doesn't work...

Amiodarone or digoxin-Amiodarone: IV 150 mg bolus +/-drip at 1 mg/min x 72 hours. Repeat bolus as tolerated to achieve rate control-Digoxin IV 5 mcg.kg load, then 2.5 mcg/kg q6hr 2x

If none of this works

Consider pharmacologic or mechanical cardioversion with TEE if no contraindications (sx>48 hours, acute stroke)

Rapid clinical assessment of afib with RVR includes

1. STAT EKG2. Remove offending agents if possible3. Evaluation and initiation oftreatment for reversible inciting factors

Purpose of STAT ekg

Confirms diagnosis, rules out aberrant conduction (Wolf parkinson white) and narrow complex tachycardia

What offending agents possibly removed

1. STOP agents with beta adrenergic properties (norepinepherine, dopamine, etc)2. Convert any pressors to phenylepherine or vasopressin

What reversible inciting factors should be evaluated for

1. Volume status: JVD, Lung crackles, edema, bedside ultrasounds to see if IVC is collapsible and to evaluate global cardiac function2. Oxygenation: ABG3. iNFECTION: CBC, CXR, UA4. Electrolytes: CMP, Mg, phos5: Other: TSH with reflex, urine drug screen6. MI: EKG, troponin q8hr 2x7. Formal TTE or TEE within 24 hours