Infectious Diseases II

what are the primary organisms on the surface of the skin?

staph and strep

What is given prior to surgery to reduce risk of infection

IV antibiotics

When should cefazolin or cefuroxime be infused before the start of surgery?

60 minutes before

If a quinolone or vanc is used for surgery, when should the infusion be started

120 minutes before

When should additional abx be given during surgery?

if the surgery is >3-4 hours or with major blood loss

When should antibiotics be stopped after surgery?

within 24 hours

what abx is preferred for most surgeries to prevent MSSA and strep infections

cefazolin

What is the abx preferred for surgery if the patient has a beta lactam allergy

clindamycin

What is the coverage needed for colorectal surgeries?

broad coverage of staph and strep along with broad gram negative and anaerobic coverage

What are the recomended abx for colorectal surgeries?

cefotetan, cefoxitin (only cephalosporins that cover anaerobes)ampicillin/sulbactam (acts the same as 2nd gen cephalosporins)ertapenem (also act the same as 2nd gen cephalosporins)ORmetronidazole + (cafazolin or ceftriaxone). Metronidazole provides the anaerobic coverage while the third gen cephalosporin provides some gram positive and gram negative coverage

What are recommended abx for colorectal surgery if the patient is allergic to beta lactams?

clindamycin (gram + cvg) + (aminoglycoside, quinolone, or aztreonam) (gram - coverage)- will not cover anaerobes unless moxi is chosen.ORmetronidazole (anaerobic cvg) + aminoglycoside or quinolone (quinolone gives more gram + coverage than aminoglycoside)

If there is mrsa risk for a surgical patient, what abx should be used?

vancomycin

Recommended abx for patients with cardiac or vascular surgery?

cafazolin or cefuroxime

recommended abx for patients with hip repair/join replacement surgery?

cefazolin

what are the classic symptoms of meningitis

feverheadachestiff neckaltered mental status

How is meningitis diagnosed?

lumbar puncture

What are possible bacterial causes of meningitis?

strep pneumoneisseria meningitisH. influenzaeListeria (among older adults)

What should Listeria be treated with for meningitis?

ADDITIONAL treatment with ampicillin

How long should a patient with meningitis ( N. meningitis and H influenzae) be treated?

7 days

How long should a patient with meningitis (s. pneumo) be treated?

10-14 days

How long should a patient with meningitis (listeria) be treated?

21 days

What can be given 15-20 minutes prior or with the first antibiotic dose to prevent neurological complications in meningitis treatment?

dexamethasone (continue for 4 days)

who is more susceptible to listeria meningitis?

neonates, age over 50, immunocompromised patients

what is preferred meningitis treatment for neonates?

ampicillin (cover listeria) + cefotaxime OR gentamicin

why cant ceftriaxone be used in neonates with meningitis?

biliary sludging and brain damage could result

What is the preferred meningitis treatment in ages 1 month to 50 years?

ceftriaxone or cefotaxime + vancomycin

What is the preferred meningitis treatment in ages over 50 or immunocompromised patients?

ampicillin+cetriaxone or cefotaxime+vancomycin

What is preferred meningitis treatment in patients with a penicillin allergy?

quinolone (moxi or levo) + vanc +/- bactrim (listeria cvg)

What are some signs of otitis media?

bulging eardrum (tympanic)otorrhea (middle ear fluid)otalgia (ear pain)tugging or rubbing ears

What is preferred for pain with otitis media?

systemic drugs like tylenol or ibuprofen rather than topical drops

how long should a patient be observed without abx with non severe otitis media

48-72 hours

What is antibiotic treatment for otitis media?

high dose amoxicillin or augmentin is first line for around a week

how much clavulanate should be with amoxicillin for otitis media

as low as possible (ratio of 14:1)- augmentin ES 600 is a good choice

otitis media patients with a nonsevere penicillin allergy should get

an oral cephalosporin (cefdinir, cefpodoxime)

nonsevere otitis media temperature

<102.2F

patients under 23 months old are automatically considered to have severe otitis media if

they have symptoms in both ears

What is the treatment dose of amoxicillin for otitis media?

80-90 mg/kg/day in 2 divided doses

What is the dose of augmentin for otitis media?

90 mg/kg/day in 2 divided doses with 6.4 mg/kg/day of clavulanate

What should be given to patients unable to tolerate oral medication with otitis media?

ceftriaxone IM or IV

What are the cephalosporin alternatives to penicillins for otitis media?

cefdinir tabscefuroxime tabscefpodoxime tabsceftriaxone IM/IV

If the first treatment of otitis media fails use

augmentin oral or ceftriaxone IM/IV

When is it considered that otitis media treatment failed? (what length of time)

48-72 hours of treatment and unimproved sx

Common cold symptoms

sneezing, runny nose, cough

common influenza sx

sudden onset feverchillsfatiguebody aches

common strep throat sx

sore throatswollen lymph nodeswhite patches on tonsils

sinusitis sx

nasal congestionfacial/ear/dental painheadache

influenza patients should only be treated is they have had sx for

under 48 hours

when should strep be treated

positive antigen diagnostic test (tonsil swab)

when should sinusitis be treated

>10 days of sx OR>3 days of severe sx (fever, face pain)ORsymptoms worsen after initial improvement

What is first line for common cold

otc products

what is first line for the flu

oseltamavir for 5 daysbaloxavir 1 dosezanamivir inhalation for five days

What is first line for strep

penicillin, amoxicillin for 10 days

what is first line for sinusitis

augmentin

when to use abx for 5-7 days for a copd exacerbation

if they have increased dyspnea, sputum volume and sputum purulenceORif they have increased sputum purulence plus increased volume or dyspneaOR if they are mechanically ventilatedwithout purulent sputum all three symptoms are needed

What is the preferred abx for a copd exacerbation

1. augmentin2. azithromycin3. doxycycline

symptoms of bronchitis

cough lasting more than 5 days

What causes acute bronchitis

viruses

What is a bacterial cause of bronchitis

bordatella pertussis

diagnosis of bronchitis is done through

ruling out other causes. chest xrays are usually not done

What is treatment for bronchitis

supportive therapy, antibiotics not recommended unless there is pneumonia. however, if it is bordatella pertussis, treat with a macrolide (azithromycin/clarithromycin) or bactrim

what are sx of pneumonia

coughpurulent sputumralestachypnea

What is the gold standard for diagnosis of CAP

chest x-ray- infiltrates- consolidations

When cap is mild it is called

walking pneumonia

what are the bacterial causes of cap

s. pneumoh. influenzaem. pneumo

what is the duration of treatment for CAP

5-7 days

what patients require broader coverage of possible drug resistant strep pneumo with cap

patients with comorbidites or are immune suppressed

What comorbidities determine cap treatment

chronic heart, lung, renal, liver diseasediabetesalcoholismmalignancyasplenia (no spleen)

when should a cap patient be treated as if they have Hap

if they received parenteral abx in the last 90 days or if they had a respiratory isolation of Mrsa or PA before

What is cap treatment for patients with no comorbidities

1. high dose amoxicillin (1gram TID) OR2. doxycyclineOR3. macrolide (azithromycin or clarithromycin if local pneumonia resistance is <25%)

What is cap treatment for patients with comorbidities

1. beta lactam + macrolide or doxy -augmentin/cefpodoxime/cefdinir/cefuroxime2. respiratory quinolone monotherapy (moxi, gemi, levo)

What is cap treatment inpatients

Antibiotics IVbeta lactam + macro lide or doxyOR respiratory quinolone monotherapy

What are the preferred beta lactams for inpatient cap treatment

Ceftriaxone, cefotaxime, ceftaroline, or unasyn

What is severe cap treatment (ICU)

Beta lactam + macrolideORbeta lactam + respiratory quinolone

If a cap patient should take if they have risk factors for MRSA

Vancomycin or linezolid

If a cap patient is at risk for PA they should take

Zoysia, cefepime, ceftazidime, imipenem/cilastatin, mereopenem or aztreonam

Onset of hospital acquired pneuomnia

Greater than 48 hours after hospital admission

Onset of ventilator associated pneuomnia

>48 hours after the start of mechanical ventilation

What are the common pathogens in hap and vap

Nasocomial pathogens. Risk for mrsa, mdr gram negative rods including PA

What is the treatment of hap and vap if the patient has a low risk for mrsa or mdr pathogens

CefepimeZosyn

What is the treatment of hap and vap if the risk for mrsa is high or postive but there is a low risk for MDR pathogens

Cefepime + vanc OR meropenem + linezolid

What is the treatment of hap and vap if the patient is at risk for both mrsa and mdr pathogens (eg iv abx in the past 90 days)

Zosyn + cipro + vancORCefepime + gentamicin + linezolid

What increases the risk for mrsa or mdr

Positive mrsa nasal swabHigh prevalence of pathogen noted in hospital unitIv abx use within the past 90 days

What are some antibiotics for PA

ZosynCefepime/ceftazidime or ceftolozane/tazobactamLevofloxacin or ciproImipenem/cilastatin or meropenemTobramycin, gentamicin, or amikacinColistimethate or polymixin b

What are the two best abx for mrsa

Vanc or linezolid

Difference between latent and active tb

Latent lacks sx but active has sx of cough/hemoptysis, fever, and night sweats that can be transmitted by respiratory droplets.

Hospitalized patients with active tb require

Isolation in a single negative pressure room with contact precautions

How is latent tb diagnosed?

Tuberculin skin test (TST) also called a purified protein derivative test (PPD)

How is a tst or ppd test administered

Intradermally and the area is inspected for induration 48-72 hours later

Who may receive a false positive TB test?

Those who have recieve the bacille calmette guerin (BCG) vaccine (used in parts of the world with high tb rates). Use an IGRA test in these patients.

What is a positive diagnosis of tb for patients in close contact of recent tb cases or patients that are immunosuppressed.

>5 mm induration

What is a postive diagnosis of tb for patients that are recent immigrants, IV drug users, moderate immunosuppression, residents/employees of high risk congregate settings like prison inmates or healthcare workers

>10 mm induration

What is a positive diagnosis of tb for patients with no risk factors

>15 mm induration

How long are patients on latent tb therapy to increase completion rates

3-4 months

Shorter latent tb therapy duration lowers a patients risk for

Hepatotoxicity

What latent tb therapy should not be used in pregnant women

Inh and rifapentine

What latent tb therapy should patients get if they adults, children over 2, and HIV positive patients? (If art does not interact)

Inh and rifapentine

How long should a patient be on inh and rifapentine for latent tb

12 weeks via directly observed therapy (DOT)

What is the preferred latent tb regimen for children of all ages and hiv negative adults?

Rifampin

How long should a patient be on rifampin for latent tb

4 months

What is a latent tb therapy that can be used in adults, children of all ages, and HIV positive patients?

Isoniazid with rifampin

How long should a patient with latent tb be on isoniazid with rifampin therapy

3 months

What is the latent tb treatment of choice for pregnant women?

INH

How long is inh (isoniazid) treatment for latent tb?

6 - 9 months

How must a positive tb test be confirmed

With a sputum culture

How is M. Tuberculosis detected

Using acid fast bacilli stain (it is slow growing and this may take up to 6 weeks)

What is "RIPE" therapy for active tb?

RifampinIsoniazidPyrazinamideEthambutol

How long should a patient with active tb be on ripe therapy

2 months

How long is the second "continuous" phase of tb treatment?

Typically it is 4 months

What are the two drugs given during the continuous phase of active tb treatment

Rifampin and isoniazid

What is used to increase medication adherence in tb infections

DOT; preferred in the homeless, drug resistant disease, adherence issues, positive sputum smears and delayed culture posivity). Patients on this can take their meds 2-3 times a week instead of daily

What are 4 side effects of rifampin

Increased lftsHemolytic anemiaPositive coombs testFlu like syndrome

What is a very important counseling point with rifampin

It can stain contact lenses and clothing orange/red (body secretions turn this color)

What can replace rifampin in patients that have major drug interactions to it

Rifabutin

What is a boxed warning for INH

Hepatitis

What decreases the risk of INH associated peripheral neuropathy?

Pyridoxine 25-50 mg po

What are 3 side effects of inh therapy

Increased lftsDrug induced lupusPositive coombs test (hemolytic anemia)

What is a contraindication to pyrazinamide

Acute gout

What are two side effects of pyrazinamide

Gout and increased lfts

What are four side effects of ethambutol

Increased lftsOptic neuritis that is dose relatedConfusionHallucinations

Rifampin will decrease concentrations of what 3 drugs

Protease inhibitorsWarfarinOral contraception

What 4 drugs should rifampin never be used with??

ApixabanRivaroxabanEdoxabanDabigatran

What is required with ethambutol treatment

Monthly vision exams

Infective endocarditis usually affects the

Heart valves

How is infective endocarditis diagnosed

Echocardiogram and a positive blood culture.

What are the three most common organisms that cause infective endocarditis

StaphylococciStreptococciEnterococci

What is empiric treatment for infective endocarditis

Vanc and ceftriaxone

What is added to the infective endocarditis regimen for synergy

Gentamicin (used when infection is difficult to eradicate, such as prosthetic valve infections or when treating resistant organisms)

Adding gentamicin to an infective endocarditis regimen puts the patient at risk for

Additive nephrotoxicity

How long should a patient be treated for infective endocarditis

4-6 weeks of IV treatment

When gentamicin is used for infective endocarditis, what is the goal peak and trough?

Because it is a gram positive infection, the peak goal is 3-4 mcg/mL and the trough goal is <1

Preferred infective endocarditis treatment when the pathogen is viridians group streptococci

Penicillin or ceftriaxone +/- gentamicin

Preferred infective endocarditis treatement when the pathogen is staphylococci (MSSA)

Nafcillin or cefazolin (+ gentamicin and rifampin if prosthetic valve)

What can be used in place of penicillins in infective endocarditis if the patient has an allergy

Vancomycin

What is the preferred treatment for infective endocarditis when the pathogen is MRSA

Vancomycin (+gentamicin and rifampin if prosthetic valve)

What is an alternative to vancomycin for mssa and mrsa infective endocarditis when the patient has a beta lactam allergy and no prosthetic valve

Daptomycin monotherapy

What patients are at high risk for infective endocarditis?

Artificial prosthetic heart valve or heart valve repaired with artificial materialHistory of endocarditisHeart transplant with abnormal valve functionCertain congenital heart defects including heart/heart valve disease

What is infective endocarditis prophylaxis for high risk patients undergoing a dental procedure

Amoxicillin 2 grams 30-60 minutes before the procedure

What is the alternative medication for endocarditis prophylaxis in patients that are allergic to penicillin

Clindamycin 600 mg ORAzithromycin or clarithromycin 500mg

What patients are often at risk for spontaneous bacterial peritonitis

Patients with cirrhosis of the liver

What is another name for spontaneous bacterial peritonitis?

Primary peritonitis

What is the first line DOC for SBP (spontaneous bacterial peritonitis)

Ceftriaxone for 5-7 days

What can be used for primary or secondary prophylaxis of SBP

Bactrim or cipro

What are the most likely pathogens for secondary peritonitis?

Strep, enteric gram negatives and anaerobes (bacteroides fragilis)

What is cholecystitis

Inflammation of the gallbladder due to a gallstone

What is cholangitis

Infection of the common bile duct

What is important to cover with intra-abdominal infections (excluding primary peritonitis)

Anaerobes

What is an antibiotic that can be added to a regimen for intraabdominal infections for anaerobic coverage?

Metronidazole

Mild to moderate 2ndary peritonitis and cholangitis treatment options

All cover PEK, anaerobes, strep +/- enterococci1. Cefoxitin2. Ertapenem3. Moxifloxacin4. (Cefazolin, cefuroxime, ceftriaxone) + metronidazole5. (Cipro or levofloxacin) + metronidazole

What are the treatment regimens for high severity 2ndary peritonitis and cholangitis?

Cover PEK, CAPES, PA, anaerobes, strep, +/- enterococciCarbapenem (not ertapenem)Pipercillin/tazobactam(Cefepime or ceftazidime) + metronidazole(Ciprofloxacin or levofloxacin) + metronidazoleCefazolin + (aztreonam or aminoglycoside) + metronidazole

What are 3 systemic signs of a skin and soft tissue infections (SSTI)

Temp > 100.4HR > 90 BPMWBC >12,000 or <4,000 cells/mm3

What are the superficial SSTIs?

ImpetigoFurunclesCarbuncles

What is an example of a nonpurulent infection?

Cellulitis

What is an example of a purulent infection?

Abscesses

What is a sign of impetigo?

Honey colored crusts on nose, mouth, hands or arms

What is preferred treatment for impetigo

Warm wet compress and a topical abx like mupirocin (bactroban)

If a patient has numerous impetigo lesions

Cephalexin (keflex) 250 mg PO QID

Folliculitis/furuncles/carbuncles treatment if there are systemic signs

Cephalexin (keflex) 500mg PO QID

Carbuncles require

Incision and drainage before abx treatment

What nonpharm treatment can help folliculitis and furuncles?

Warm compresses

If a patient with folliculitis/furuncles/carbuncles is nonresponsive to keflex, change to what drug? (2 options)

MRSA coverageBactrim Doxycycline

Mild cellulitis should be treated wiht

Abx active against strep +/- MSSACephalexin

What is mild to moderate purulent abscess caused by usually

CA MRSA

What is the treatment of mild to moderate abscess if there is systemic signs or multiple sites?

1. I & D2. Bactrim or doxyMRSA coverage

Severe purulent SSTI treatments

Antibiotics with MRSA coverage1. Vancomycin2. Daptomycin3. Linezolid

Necrotizing fascitis treatment

Vancomycin + beta lactam (piptazo, imipenem cilastatin, meropenem)

Diabetic foot infections are usually

Polymicrobial so broad spectrum coverage

What can a diabetic foot infection lead to ?

Osteomyelitis

When no mrsa coverage is needed how should a diabetic foot infection be treated?

UnasynZosynCarbapenemTigecycline (last line)Moxifloxacin

When mrsa or Pa coverage is needed, what diabetic foot infection treatment should be chosen?

Vanc plusCeftazidim/cefepime/zosyn/aztreonam/carbapenem (not ertapenem)Consider adding metronidazole if ceftazidime/cefepime/aztreonam is selectiveAlternatives to vanc are dapto or linezolid

What is the duration of treatment for nonsevere diabetic foot infection

7-14 days

What is the duration of treatemnt for severe deep tissue diabetic infection

2-4 weeks

What is duration of treatment for severe limb threatening or bone/joint infection

4-6 weeks

What are the signs of a lower uti (cystitis)

Urgency/frequencyNocturiaDysuria (painful urination)Suprapubic heavinessHematuria

What are the signs of an upper uti (pyelonephritis)

Flank/painAbdominal pain, nausea, and vomitingFever/malaise

What are the signs of vaginal candida infections

Extremely itchy with white thick discharge

When is a uti considered noncomplicated

NonpregnantPremenopausal women with no urologic abnormalities or comorbities

When is a uti considered complicated

MaleIndwelling catheterNeurogenic bladdder

How is a uti diagnosed

With a urinalysisPyuria (wbc over 10)And bacteruria (>10^5 bacteria/mL in asymptomatic pts, >10^3 bacteria in symptomatic males and >10^2 in symptomatic females and cathetarized patients

What is the most common pathogen for acute uncomplicated cystitis?

E.coli

What is the drug of choice for acute uncomplicated cystitis? there are 2

Macrobid (nitrofurantoin) 100mg po bid with food for 5 daysORBactrim DS tablet for 3 days

Who should not have macrobid

Crcl <60

Who should not have bactrim

Sulfa allergy or high e.coli resistance

What are the best abx for pregnancy uncomplicated cystitis

Cephalexin or amoxacillin

What can be added to uti treatment to relieve dysuria

Phenazopyridine (pyridium)

What is treatment for acute uncomplicated pyelonephritis moderately ill outpatient (PO) if local quinolone resistance is <10%

Ciprofloxacin 500mg po BID for 7 daysLevofloxacin 750 mg po daily for 5 days

For acute uncomplicated pyelonephritis treatment if local quinolone resistance is >10%

CeftriaxoneSMX/TMPBeta-lactam

Treatment for acute uncomplicated pyelonephritis for severely ill hospitalized patient (IV)

Initial: cipro or levofloxacin OR gentamicin +/- ampicillin/zosyn/ceftriaxone OR a carbapenem. Treat for 14 days

What is the treatment for a complicated uti

Carbapenem if esbl producing bacteria are present. Treat similar to pyelonephritis

What is the brand name of phenazopyridine?

Pyridium, azo

How long can phenazopyridine be used

2 days max

What is a side effect of phenazopyridine?

Red orange urine coloring and other body fluids like contact lenses/clothes can be stained

How should phenazopyridine be taken?

With food to minimize stomach upset and 8oz of water

What is the preferred treatment of bacteruria in pregnancy

Augmentin or an oral cephalosporin

What uti treatment should be avoided in pregnancy

Quinolones due to toxicity

What causes 80-90% of travelers diarrhea cases

E.coli

What are less common causes of travelers diarrhea

Campylobacter jejuni, shigella spl and salmonella

What is a sx of travelers diarrhea

Dysentery (bloody diarrhea)

What is the preferred abx for dysentary

Azithromycin

What is the preferred abx if blood diarrhea is not present

Quinolones, rifaximin

Preferred travelers diarrhea treatment if fever, blood in stoools, pregnant, or pediatric

Azithromycin 1000mg PO x1 or 500 mg PO daily x1-3

Preferred travelers diarrhea treatment if no fever, no blood in stools, not pregnant, or not pediatric

Cipro, levofloxacin, oflaxacin, rifaximin

What does cdiff release

Toxin A and B that attack the intestinal lining

What are the sx of cdiff

Abdominal cramps, profuse diarrhea, fever

What can cdiff lead to

Pseudomembranous colitis which can lead to toxic megacolon

What should not be used for cdiff

Antidiarrheal medication

If a patient is having multiple loose stool on an antibiotic

Discontinue abx as soon as possible

How is cdiff diagnosed

Positive cdiff stool toxin test or positive c diff culture

What is considered non severe for cdiff

Wbc <15000 and scr <1.5

What is considered severe for cdiff

Wbc >15000 scr >1.5

What is considered fulminant/complicated cdiff

Signifiant systemic toxic effects present (hypotension, shock, ileus or toxic megacolon)

What is the treatment for the 1st episode of a nonsevere or severe cdiff

VAN 125 my PO QID for 10 days ORFDX (fidaxomycin, dificid) 200mg PO BID for 10 days

What is a treatment for nonsevere cdiff if vanc and fidaxomycin are not available

Metronidazole 500 mg PO TID x 10 days

What is cdiff treatment for the 1st epidode of fulminant/complicated disease

Vanc 500 mg PO/NG/PR QID + metronidazole 500mg IV q8h

What is the treatment for the 1st recurrence of cdiff if the patient was given metronidazole for the first episode

Vanc 125 mg PO QID x 10 days

What is the treatment for the 1st recurrence of cdiff if the patient was given vanc for the initial episode

Fidaxomicin 200 mg po BID x 10 days

If vanc or fdx are used for the initial episode for cdiff, what should be given if it reoccurs?

Vanc tapered and pulsed regimen. Ex: 125mg po QID 10 days, BID 1 week, daily x1 week, then 125 mg every 2-3 days for 2-8 weeks

Sx of chalmydia

Discharge, no sx

Sx of gonorrhea

Discharge, no sx

Sx of syphilis

Painless, smooth genital sores

Sx of hpv

Genitval warts or no sx

Bacterial vaginosis sx

Discharge clear/white/grey; fishy odor; ph >4.5; little or no pain

Trichomoniasis sx

Discharge yellow/green; soreness, pain with ix

What is the doc for syphillis

Bicillin LA

What is the dose used for syphillis

Bicillin LA 2.4 million units IM x 1

What is an alternative syphillis treatment in patients allergic to beta lactams

Doxycycline

What patients allergic to beta lactams with syphillis should still receive bicillin la?

Pregnant patients and HIV positive patients with poor compliance/follow up

How is syphilis diagnosed?

Rapid plasma reagin (RPR), venereal disease research lab (VDRL) blood test

What is the dosing for syphillis that has been going on for a year or unknown duration?

Bicillin La 2.4 million units IM weekly for 3 weeks

What is the treatment for neurosyphilis and congenital syphilis

Penicillin G aqueous crystalline

What is the doc for gonorrhea

Ceftriaxone + azithromycin (preferred) or doxy

What is the dosing of ceftriaxone for gonorrhea

250 mg IM x 1

What is the dosing of azithromycin for gonorrhea

1 g po x 1

What is the doc for chlamydia?

Azithromycin

What is the dose of azithromycin for chlamydia

1g po x1

What is the doc for bacteria vaginosis

Metronidazole or metronidazole 0.75% gel

What is a counseling point for bacterial vaginosis

Females with bacterial vaginosis should not douche

What is the doc for trichomoniasis

Metronidazole

What is the dose of metronidazole for trichomoniasis

2 g PO x1

What should a pregnant woman take for trichmoniasis

Metronidazole

What is the doc for genital warts (HPV)

Imiquimod cream

What is Aldara (imiquimod cream) also approved for besides hpv?

For superficial basal cell carcinoma

How can hpv be prevented

Gardasil vaccine

Gardasil reduces risk of

Cervical and other cancers

Gonorrhea treatment with also treat what?

Chlamydia. They both use azithromycin 1g x1

How should a pencillin allergy be confirmed in a pregnant woman with syphillis

Confirm with skin prick test

What are rickettsial diseases

Diseases carried by ticks, fleas, and lice

What is the most fatal illness caused by ticks/fleas/lice

Rocky mountain spotted fever

What is the treatment of rocky mountain spotted fever

Doxycyline (also the doc for pediatric pts)

What is the doc for lyme disease

Doxy

How can you get typhus or ehrlichiosis?

From ticks/fleas/lice

How is tularemia treated?

Gentamicin or tobramicin

How is lyme disease diagnosed

Enzyme immunoassay (EIA)