main symptoms of tuberculosis
-appetite loss, fatigue-chest pain, coughing blood, productive-prolonged cough-night sweats, pallor
isoniazid
-1st line therapy in treatment of active tuberculosis-prophylaxis for exposed individuals or latent TB
isoniazid [contraindication]
-acute hepatic disease, alcoholism-caution: severe renal impairment, diabetes
isoniazid [side/adverse effects]
-hepatotoxicity-peripheral neuropathy-hyperglycemia-dizziness, tremors, blurry vision, seizure-photosensitivity!-GI: nausea, vomiting, constipation, dry mouth-thrombocytopenia, agranulocytosis, anemia
isoniazid requires
-frequent medical follow up and/or direct observation-notify provider for symptoms of hepatitis, neuropathy-B6 supplementation
nystatin
polyene antifungal; treats candida infection by disrupting fungi of cell membrane
nystatin [side/adverse effects]
-GI: nausea, vomiting, diarrhea
fluconazole
treatment of fungal infection including candida; increases fungal cell membrane permeability
fluconazole [side/adverse effects]
-GI: nausea, vomiting, diarrhea, anorexia-hepatotoxicity-rash