Drugs CH 3

antagonism

situation in which the response to one drug is decreased in the presence of another drug

synergism

when two drugs together produce a greater effect than either drug produces (involves both potentiation and addiction)

pharmacological antagonist

is a drug that has a definite affinity for a receptor but has little or no efficacy after being bound to it.

competitive antagonism

if the agonist is capable of dissociating from the receptor

noncompetitive antagonism

is incapable of being dissociated or displaced from the receptor.