StephanieLee

Tissue

is a collection of similarcells that performs a general function

4 Primary types of Tissues

Epithelial: cover and line body organs and form the glands.Connective: connect between other tissues, support the shape and integrity of organs, transport substances, and protect soft structures.Muscle: provide movement.Nervous: manage homeostasis by rapid communication

Epitheluim

Composed of close-fitting cells often bridged together, allowing little or no blood vessels through (= avascular). Includes two main types: covering and lining epithelium and glandular epithelium.

2 major functions of epithelium tissue

Protection: epithelium forms a sheet-like barrier.Control of permeability: forms a filter, allowing selective movement of substances.Secretion: some cells secrete products.

Desmosomes

lock cells together byprotein and intercellular �glue�

Tight junctions

fuse the cell membranes of two adjacentcells together

Gap Junction

connect two cells by channel proteins, establishing a tube-like bridge

Covering and Lining Epithelium

Forms a sheet-like covering orlining. It is categorized based on 1) shape of its cellsand 2) number of cell layers. The sheet of cells lieupon a layer of protein, called the basement membrane.

Simple squamous epithelium

Flattened cells arranged in a single layer.All cells contact the basement membrane.Often located where diffusion must occur.Examples: lining of blood vessels and lymphatic vessels,walls of capillaries, walls of alveoli, lining of body cavities.

Simple cuboidal epithelium

Single layer of cube-shaped cellsAll cells contact the basement membraneOften forms a small tube, or duct, carrying fluids.Cells may contain cilia or microvilli on their apical surface.Examples: forms ducts in the kidneys, liver, andassociated with glands.

Simple columnar epithelium

Single layer of elongated column-shaped cells.Each cell contains a nucleus located near the basement membrane.Cells may include microvilli along their apical surface.Example: lines digestive tract.

Stratified squamous epithelium

Multiple layers of cells that become flattened as they approach the apical surface. Basal layer of cells are columnar or cuboidal in shape.Serves as a protective, almost impermeable barrier.Examples: forms the outer layer of the skin, lines penetrations through the body surface such as the digestive tract and upper respiratory tract.

Pseudostratified columnar epithelium

Appears to be multiple layered but is not.All cells contact the basement membrane; therefore it is a simple epithelium.Cells often include cilia along the apical surface. The cilia beat rhythmically to form a conveyor belt of mucus. Abbreviated PSCC epithelium.Forms an importantprotective barrier.Example: lines thetrachea and bronchi

Transitional epithelium

Multiple-layered arrangement of cube-shaped cellsCells have capacity to expand and shrink in size, similar to crepe paper.This gives the tissue the ability to stretch and contract back.Example: lines the urinary bladder and ureter, enabling these organs to expand and contract with changing fluid volumes.

Glandular Epithelium

Consists of closely packed cells that are specialized tosecrete a product to form glands.

2 groups of glandular epithelium

Exocrine glands: secrete products into ducts that openonto body surface or within body cavitiesEndocrine glands: secrete products, called hormones, into theextracellular space, where it diffuses into bloodstream.

Connective Tissue

Composed of relatively few cells suspended in an intercellular soup of cell products.Most abundant tissue in the body; includes tendons, ligaments, bone, cartilage, and blood.Functions in:-Support-Protection-Communication-Storage-Blood cell production-Repair

Connective tissue cells produce and secrete the intercellular material, composed of

Ground substance = sugar-protein molecules in a watery mediumMatrix of protein fibers = collagen, elastin, and reticulin.

Connective Tissue Proper

Present throughout the body, between and within most organs. Intercellular material is produced by cells called fibroblasts.

Loose connective tissue (areolar tissue)

Intercellular material is a thickened fluid, made thick by a loosely arranged matrix of all 3 types of protein fibers.Cells include:-Fibroblasts -White blood cells, including macrophages

Adipose Tissue

Specialized for energy storage in the form of fat.Dominated by cells = adipocytes, which contain a large droplet of lipid in the cytoplasm.Functions in energy storage, insulation, and padding. Example: most abundant in the superficial fascia, where it is called subcutaneous fat.

Dense Connective Tissue

Consists of a dense intercellular substance, composed of a matting of protein fibers packed tightly together; mostly collagen fibers.

Dense Irregular connective tissue

Fibers are not parallel, but branch to form a dense matting.Little ground substance.Fibroblasts are squeezed between bundles of collagen.Example: main component of the skin�s dermis; forms scar tissue

Dense Regular Connective tissue

Fibers are in parallel arrangement.Collagen is so dense it allows almost no ground substance.Fibroblasts are squeezed between collagen bundles.Example: forms tendons (attach bone to muscle) and ligaments (attach bone to bone)

Cartilage

A hard connective tissue with flexibility. The hard quality is provided by a dense matrix of protein fibers within a thickened ground substance. Its density prevents intrusion of blood vessels. Its cells, called chondrocytes, lie embedded in chambers called lacunae. Nourishment is possible by way of an outer layer of dense connective tissue called the perichondrium and the diffusion of substances through the ground substance.

Hyaline Cartilage

?Most abundant cartilage; firm and supportive.?Blueish-white, almost opaque?Collagen fibers not visible due to dense groundsubstance.?Ground substance composed of large carbohydratemolecules called chondroitin sulfate, and glycoproteins.?Examples: forms the template of bones, covers bonesurfaces where they form joints, in respiratory tract (larynx, trachea,bronchi), in ribcage, in the nose.

Elastic Cartilage

?Elastic fibersvisible as dark lines branching throughout the matrix, giving it elasticqualities.?Ground substance notas dense as in hyaline cartilage.?Example: ears,epiglottis.

Fibrocartilage

?Matrix containsvisible bundles of collagen.?Chondrocytes within lacunae inclusters between collagen bundles.?Example:shock-absorbing, slightly flexible cushion within some joints, including intervertebral discs and pubic symphysis

Bone

Known for its hard, durable features, it provides a structural frame for the body and a muscle attachment site. It is also called osseous tissue, and functions in protection, support, and blood cell formation. Bone matrix is composed of collagen fibers and a mineralized ground substance. The bone cells, called osteocytes, are mainly isolated within chambers called lacunae, and obtain nutrients through tiny fissures through the ground substance from an outer membrane called the periosteum.

Compact Bone

Densely packed matrix laid down in concentric layers called lamellae.Osteocytes in lacunae are sandwiched between lamellae and communicate with each other and a central osteonic canal by way of fissures called canaliculi. The cylindrical arrangement is called an osteon (haversian system).Forms the outer layer of all bones.

Spongy Bone

?Matrix is arranged toform small thin plates that form an interbranching network called trabeculae.?Osteocytes within lacunae maybe found in each plate, surrounded by solid matrix.?Between the plates isa soft, blood-forming tissue called red marrow.?Found along theinside surface and fills the ends of most bones.

Fluid Connective tissue

Some connective tissues include a matrix with a ground substance that is in the liquid state with dissolved proteins. It also includes living cells. It functions in transportation of substances.

Blood

?The liquid ground substance is plasma,and the cells include red blood cells, white blood cells, and platelets.?Found within blood vessels and the heart.

Lymph

?The liquid ground substance is lymph, and the cellsinclude white blood cells (only).?Found within lymphatic vessels and other lymphaticorgans (spleen, thymus, lymph nodes, tonsils, etc.).

Muscle Tissue

Composed of cellsspecialized to contract, or shorten in length. The result ofcontraction is the production of movement and heat.The cells are tightlypacked; there is little or no intercellular material between cells.

3 types of muscle tissue

Skeletal muscle tissue: attached to bones and produces body movement. Cells have striations, and can respond to conscious control. Cells are very long, forming muscle fibers.Smooth muscle tissue: in the walls of hollow visceral organs, such as digestive tract organs, bronchioles, bloodvessels. Cells are not striated, and do not respond to conscious control. Cells are short and spindle-shaped.Cardiac muscle tissue: in the walls of the heart. Cells are striated, but do not respond to conscious control. Cells are short and block-shaped.

Nervous Tissue

Composed of cellsspecialized to either conduct an electrochemical signal or support cells thatconduct.Cells are capable ofexcitability and conductivity.

2 cell types of nervous tissue

Neurons - excitable and conduct impulses. Each includes a central cell body, andextensions known as dendrites and axon.Neuroglia � supportive cells; 90% of nervoustissue.Form the brain,spinal cord, and peripheral nerves; also contribute to sensory organs.

Membrane

The simplest combination of 2 or more types of tissues. Membranes structurally divide body compartments, linecavities, and cover visceral organs. They provide protection and convey blood vessels, lymphatics, and nerves. Usually consist of a superficial layerof epithelium and a deep layer of connective tissue proper.(4 types)

Cutaneous Membrane

Also known as the skin, it consists of an outer layer ofepithelium (simple squamous ep.) and an inner layerof connective tissue (dense irregular c.t.). Covers the body to form the surface, providing animportant protective barrier.

Serous Membrane

Line the internal surfaces of the thoracic and abdominopelvic cavities and formthe outer layer of many visceral organs.A thin layer of simple squamous ep.with a basement membrane of loose c.t.Cells secrete a watery lubricating fluid known as serousfluid.

Mucus Membrane

Line the internal surfaces of body openings and internalchannels (digestive tract, respiratory tract, reproductive tract). Lubricate and protect.A layer of epithelium, often simple columnar orstratified squamous ep., with a basementmembrane of loose c.t.Mucus cells within the epithelium secrete mucus, whichlubricates and protects.

Synovial Membrane

Line the inside wall of cavities surrounding certainjoints, such as the elbow, knee, and shoulder.Lack epithelium; contains cells that secrete synovialfluid to provide lubrication of the joint.