Biology 100

Procaryote Cells

Cells without true nucleus. Ex. Bacteria

Ribosomes

Part of procaryote cellSite of protien synthesis

Eucaryotic Cells

Cells with a true nucleus

Chromatin

Part of eucaryotic cellsFibers of DNA

Vacuoles

DigestionChemical storageH2O balenceCell enlargement

Chloroplast

Converts solar energy to sugar molecules

Mitochondria

Powerhouse; Convert energyEx. Glucose => ATPWhere most ATP is producedWhere most cellular respiration occurs

Nucleolus

Mass of chromatin, DNA, RNA, & protiensWhere ribosomes are costructed

Lysosomes

Digest materialsFuse with white blood cells to destroy bacteriaTransport vehicle

Rough Endoplasmic Reticulum

Ribosomes on membraneSite of protien synthesisWhere cell membrane is produced

Smooth Endoplasmic Reticulum

Found in the liverProduction of lipidsDetoxification of drugs, degrades alcohol & cholesterolFormation of hormones & steroids Stores calcium ions in muscles

Goolgi Complex

Distribution CenterRecieves, stores, modifies, & distributes chemical products of the cell

Diffusion

Particles spread out from more concentrated areas to less concentrated across a permeable membrane

Osmosis

Passive transport of H2O

Facilitated Diffusion

Protiens move substances thru cell walls

Active Transport

2 Types:EndocytosisExocytosis

Endocytosis

Moves particles in

Exocytosis

Moves particles out

Phagocytosis

Cellular eating

Hypertonic

Higher concentration of solutes

Hypotonic

Lower concentration of solutes

Isotonic

Equal concentration of solutes

Potential Energy

Capacity to do work

Kinetic Energy

Energy to actually do work

2 Types of Chemical Reactions

Endergonic ReactionsExergonic Reactions

Endergonic Reactions

Require energy Ex. Photosynthesis

Exergonic Reaction

Releases energyEx. Wood burning

Cellular Respiration Definition #1

Creating energy from food molecules by your cells

Cellular Respiration Definition #2

Cell takes apart a glucose molecule & taps the energy carried by electrons being rearranged when old bonds break & new ones form

Cellular Respiration Formula

C6H12O6 + 6O2 --> 6CO2+ 6H2O + ENERGY (ATP)

Redox Reactions

Reductions = addition of electronsOxidation = loss of electrons

3 Kinds of Work Cells Perform

Mechanical - movement of ciliaTransport - brain cells pump ions across their membranesChemical - linking amino acids -> protiens

3 Stages of Cellular Respiration

GlycolysisKreb's CycleElectron Transport Chain

Glycolysis

Happens in cytoplasm Glucose => Peruvic Acid + Energy (ATP, NADH)

Kreb's Cycle

Happens in mitochondria Peruvic Acid -> C-C-C ->CO2 kicked off C-C(acetic acid) + CoEnzyme A + ATP

Electron Transport Chain

Happens in mitochondria membraneStores electrons from stages 1 & 2 to make most cells ATP

Long Wavelengths...

Have less energy than shorter wavelengths

Photosynthesis

Ultimate source of food for every organismThe most important chemical process on Earth

Photosynthesis Formula

6CO2 + 6H2O --> C6H12O6 + 6H2O + 6O2

Photosynthesis Stage #1 - Light Reaction

Occurs in thylakoid membraneAbsorbs solar energyConverts to chemical energy stored in ATP & NADHDoesn't produce sugar, only energy!

Sexual Reproduction

Union of sperm & eggCreates genetic variation

Asexual Reproduction

Production of offspring by a single parent without egg & spermProduces exact genetic replicasAlso called binary fussionEx. Bacteria reproduce this way

Mitosis

Daughter cells with same # of chromosomesIdentical copies

Meiosis

Reduces # of chromosomes by 1/2

Homologous Chromosomes

A pair of chromosomes that look alike & carry the same genes for the same trait (exception, sex chromosomes)

Eucaryote Reproduction

Have true nucleusWhen nucleus is not dividing DNA is a tangled mass of thin threads called chromatin When it starts dividing DNA becomes highly coiled & condensed called chromosomes

3 Processes of Cell Division

Interphase - Cell prepares to replicateMitosis - Nuclear division resulting in the same # & kind of chromosomes in daughter cells as parent cells Cytokinesis - Division of cytoplam

Interphase G1

Period before DNA synthesis increases in: protiens, organelles, size, MTOC & centriole pairs appear

Interphase S

DNA synthesis begins resulting in two sister chromatids (single DNA strand)

Interphase G2

Time from DNA synthesis to the onset of cell division

4 Main Stages of Mitosis

Prophase Metaphase Anaphase Telophase

Prophase

Chromatin fibers condense, chromosomes visableNucleolus disappearsMTOC's begin to move towards polesMiotic spindle grows out of nuclear membrane fragment

Metaphase

Sister chromatids line up on equator of cellMTOC's at poles Spindle apparatus fully formed* Centromere - where sister chromatids are connected

Anaphase

Centromeres divide & chromosomes seperateDaughter chromosomes move towards poles

Telophase

Nuclear envelope forms around daughter cellsNucleolis reappearsChromosomes become diffused chromatin

Cytokinesis

Cell division

Haploid

Cells with a single set of chromosomes

Gamate

Sex cells with haploid # of chromosomesEx. Sperm & eggs

Diploid

Homologous set of chromosomes (2 chromosomes)

Stages of Meiosis I

InterphaseProphase IMetaphase IAnaphase ITelophase ICytokinesis

Interphase I

Chromosomes replicate = 2 genetically identical sister chromotidsMTOC's with centriol pairs appear

Prophase I

Most complex stage90% of cell reproduction cycle occurs hereHomologous chromosomes with identicals sister chromatids pair up forming a tetrad (4 chromotids)

Metaphase I

Tetrads line up on metaphase plate

Anaphase I

Chromosomes moving toward poles

Telophase I & Cytokinesis

Chromosomes arrive at polesNuclear envelope appearsCytokinesis shows clevage furrow

Meitosis II

Is basically like a miotic division without chromosome replication

Prophase II

Chromosomes condenseSpindle formsNuclear envelope fragments

Metaphase II

Chromotids line up on metaphase plate

Anaphase II

Sister chromotids seperate

Telophase II & Cytokinesis

4 haploid daughter cells (sperm or egg)

Crossing Over

Original chromosomes break apart & exchange genetic informationHappens in prophase

Independent Assortment

Chromosomes align independently (randomly) at metaphase plateMaternal or paternal chromosomes may be oriented toward either poleHappens in metaphase

Cancer

Normal cells in your body die after approximately 50 replications, cancer cells are immortal

Cancer Cells

Don't have a properly functioning cell cycle control system therefore divide excessivelyUncontrollable growth

Tumor

Excessive cell growth resulting in an abnormal mass of cells

Benign Tumor

Abnormal mass of normal cells that remain at original site in body

Malignant Tumor

Cancerous!Capable of spreading out to surrounding tissues or other parts of body

Metastasis

Spread of cancer cells beyond original site

Carsinoma

Originate on external or internal coveringsEx. Skin, intestinal lining

Sarcoma

A rise in tissueEx. Bone, muscle

Lukemia & Lymphomias

Cancers of the blood foring bone marrow, spleen, lymph nodes

Oncogene

Genes that cause cancer

Protooncegene

Have potential to become oncogenes

Embryonic Stem Cells

Taken from 5 day old blastocyst (blastula)Will differentiate into any type of cell

Adult Stem Cells

Scarcer that embryonic stem cellsLimited to tissue of origin

Umbilical Cord Cells

Stem cells from newbornProduce only blood cells (red & white & other parts of immune system