13 ANS drugs

Autonomic nervous system (ANS) function:

Governs involuntary actionsSympatheticParasympatheticNeurotransmitters


Fight or Flight


rest and digest

Drugs that affect ANS

1.Adrenergics (sympathomimetics)2.Adrenergic blockers (alpha and beta blockers)3.Cholinergics (parasympathomimetics)4.Cholinergic blockers (anticholinergics)


Fright, fight, and flight

Sympathetic nervous system (SNS)

Neurotransmitters � catecholamines

�Epinephrine (adrenaline)�Norepinephrine�Dopamine

True or false

adrenergics mimic actions of the SNS
True False


Adrenergic Uses

1.Restoring rhythm in cardiac arrest2. Elevating blood pressure in shock3.Constricting capillaries4.Dilating bronchioles in acute asthmatic attacks, bronchospasm, or anaphylactic reactions5.Performing ophthalmic procedures

adrenergic side effects

Palpitations, nervousness/tremors, tachycardia, arrhythmias, hyperglycemia, hypertension, HA/insomnia, tissue necrosis*, anginal pain

Adgrenerics Contraindications or extreme caution

angina, coronary insufficiency, HTN, arrhythmias, angle closure glaucoma, organic brain damage, hyperthyroidism

adgrenergics caution

Carefully check dose (small amounts only), Give SubQ, IM (deltoid), or IV.

adgrenergic administration

SubQIM (deltoid)IV

CNS drugs, beta- adrenergic blockers, alpha adrenergic blockers are all examples of interactions for _______?


Block action of SNS, Alpha-adrenergic blockers, Beta-blockers, Propranolol (Inderal) are all actions of _______?

adgrenergic blockers

Uses of beta-blockers

�Hypertension�Cardiac arrhythmias�Angina pectoris�Migraine headache

Side effects of Adgrenergic blockers

Hypotension, bradycardia, fatigue or lethargy, N/V, hypoglycemia, confusion.

slow heart rate is a side effect of

adgrenergic blockers

true or false

patients should rise slowly to avoid postural hypotension
True False


cholenergics are used for:

Parasympathetic nervous system

Acetylcholine is a type of

- neurotransmitter

drugs that mimic the PNS


these actions such as

�Increased GI peristalsis
�Increased contraction of urinary bladder
�Increased secretions (sweat, saliva, gastric juices)
�Increased skeletal muscle strength

are all examples of

cholinergic actions

these actions (Decreased intraocular pressure, Constriction of pupils, Slowing of heart)

are examples of

cholinergic actions

examples of cholinergic uses

�Non-obstructive urinary retention�Non-obstructive abdominal distention�Myasthenia gravis � neuromuscular disorder,muscle weakness (activity).�Open-angle glaucoma

a cholinergic antidote

atropine sulfate IV

N/V/DContraindications or ex, muscle cramps/weakness, slow pulse/BP, sweating, respiratory depression, bronchospasm are all examples of ________?

cholinergic side effects

what type medicatons should cholinergics not be used with?

antibiotics and heart meds

actions such as these are examples of

�Drying (All secretions decreased)
�Decreased GI and genitourinary (GU) motility
�Dilation of pupils

cholinergic blockers

�Antispasmodic and antisecretory for GI or GU
�Preoperative and preanesthetic application
�Neuromuscular block and other spastic
�Antidote for insecticide poisoning,
cholinergic crisis, or mushroom poisoning

cholinergic blocker

Antidote for insecticide poisoning,
cholinergic crisis, or mushroom poisoning

cholinergic blocker

used for preoperative and preanesthetic application

cholinergic blocker

used in emergency treatment of bradycardia and atrioventricular heart block with hypotension

cholinergic blocker

dilation of pupils


Patient education for ______

Awareness of possible side
effects, dry mouth, blurred vision.

cholinergic blocker

Contraindications or extreme caution for _______

(w/use of atropine) Asthma, COPD, angle-closure, GI or GU obstruction, arrhythmias, HTN, hypothyroidism, hepatic or renal disease.

cholinergic blocker

Side effects of ______

dry mouth, urinary retention, constipation, confusion tachycardia. blurred vision

cholinergic blocker

anticholinergic drug


_____ increase gastrointestinal peristalsis and contractions of the urinary bladder


cardiac arrythimias, angina, and migraines can be treated with _______

adrenergic blockers

neostigmine a cholinergic is used to treat what neuromuscular disease

myasthenia gravis

clients taking beta blockers should be instructed to ________ to avoid postural hypotension

arise slowly from a reclining position

how can the bodys sympathetic nervous system best be described

the emergency system

how can the parasympathetic nervous system best be described

resting and digesting system

epinephrine, norepinephrine, dopamine can all examples of


which colinergic blocker is used to prevent motion sickness

Scopalamine(ship = motion sickness)

____ nerve conducts impulses in the thigh and lower leg


the major nerve in the PNS

vagus(veggies= rest and digest)

preoperative medication to dry secretions and reduce gastric activity are all uses for

cholinergic blockers

a cholinergic drug used to treat urinary retention not associated with benign prostatic hypertrophy


drugs that mimic parasympathetic responses


drugs that mimic the parasympathetic actions


mediator liberated and synthesized by parasympathetic nerve fibers


cholinergic used to lower intraocular pressure in glaucoma


____ dilate to allow a greater oxygen supply


adrenergic administered for severe shock


classic example of a cholinergic blocker


adrenergic blocker used for anginas, arrythmias, and migraines


most commonly used adrenergic blockers are known as _____ and ______

alpha and beta