Pharmacology-14 Opioid Analgesics


Strong Agonists Fentanyl


Duragesic Pain High affinity for Mu receptors Respiratory depression, constipation, abuse


Strong Agonists Hydromorphone


Dilaudid Pain High affinity for Mu receptors Respiratory depression, constipation, abuse


Strong Agonists Meperidine


Demoral Pain High affinity for Mu receptors Respiratory depression, constipation, abuse


Strong Agonists Methadone


Dolophine, Methadose Pain High affinity for Mu receptors Respiratory depression, constipation, abuse


Strong Agonists Morphine


Roxanol, Statex Pain High affinity for Mu receptors Respiratory depression, constipation, abuse


Mild-to-Moderate Agonists Codeine


Pain Not as high affinity to opioid receptors. Constipation, less risk of respiratory depression.


Mild-to-Moderate Agonists Hydrocodone


Hycodan Pain Not as high affinity to opioid receptors. Constipation, less risk of respiratory depression.


Mild-to-Moderate Agonists Oxycodone


Oxycontin Pain Not as high affinity to opioid receptors. Constipation, less risk of respiratory depression.


Mild-to-Moderate Agonists Propoxyphene


Darvon, Darvocet Pain Not as high affinity to opioid receptors. Constipation, less risk of respiratory depression.


Mixed Agonist-Antagonist Butophanol


Stadol Pain, treating opioid addictions Partially activates mu receptors, antagonist to kappa Hallucinations


Mixed Agonist-Antagonist Buprenorphine


Buprenex Pain, treating opioid addictions Partially activates mu receptors, antagonist to kappa Hallucinations


Mixed Agonist-Antagonist Nalbuphrine


Nubain Pain, treating opioid addictions Partially activates mu receptors, antagonist to kappa Hallucinations


Mixed Agonist-Antagonist Pentazocine


Talwin Pain, treating opioid addictions Partially activates mu receptors, antagonist to kappa Hallucinations


Antagonists Nalmefene


Revex Not for pain,Opioid overdose and addiction Block all opioid receptors, especially mu. Displace opioid agonists Reverse respiratory depression in 1-2 minutes


Antagonists Naloxone


Narcan Not for pain,Opioid overdose and addiction Block all opioid receptors, especially mu. Displace opioid agonists Reverse respiratory depression in 1-2 minutes


Antagonists Naltrexone


ReVia Not for pain,Opioid overdose and addiction Block all opioid receptors, especially mu. Displace opioid agonists Reverse respiratory depression in 1-2 minutes