Digestive System


Two groups of organs:


alimentary canal (gastrointinal or GI tract)accessory digestive organs


Alimentary canal (gastrointestinal or GI tract) includes:


mouthpharynesophagusstomachsmall intestinelarge intestine


Alimentary canal (gastrointestinal or GI tract) does what to food?


digest and absorbs food


Accessory digestive organs include:


teethtonguebladderdigestive glands


Digestive glands include:


salivary glandsliverpancreas


6 essential activities of digestive processes:


ingestionpropulsionmechanical digestionchemeical digestionabsorptiondefecation


Adjacent segments of alimentary tract organs alternately contract and relax, which moves food along the tract distally.


peristalsis


Nonadjacent segments of alimentary tract organs alternately contract and relax, movign food forward then backward. Food mixing and slow food propulation occurs.


segmentation


Serious membrame of the abdominal cavity.


peritoneum


Peritoneum includes:


visceral peritoneum: on external surface of most digestive organspartietal peritoneum: lines the body wall


Peritoneal cavity is found _____ the two _____. And _____ lubricates mobile _____.


betweenperitoneumsfluidorgans


Double layer of peritoneum.


mesentary


Two functions of the mesentary:


routes for blood vessels, lymphatics, and nervesholds organs in place and stores fat


Organs that lie posterior to the peritoneum.


retroperitoneal


Organs that are surrounded by the peritoneum.


intraperitoneal (peritoneal)


Fout basic layers (tunics):


mucosasubmucosamuscularis externaserosa and/or adventitia


The mucosa lines the _____.


lumen


Three functions of mucosa:


secretes mucus, digestive enzymes and hormonesabsorbs end products of digestionprotects against infectious disease


Three sublayers of mucosa:


epitheliumlamina propriamuscularis mucosae


Simple columnar epithelium and mucus-secreting cells; may secrete enzymes and hormones (e.g., in stomach and small intestine)


epithelium mucosa


Two functions of epithelium mucosa:


protects digestive organs from enzymeseases food passage


Loose areolar connective tissue.


lamina propria mucosa


Lamina propria mucosa are capillaries for _____ and _____; also lymphoid _____.


nourishmentabsorptionfollicles


Smooth muscle that produces local movements of mucosa.


muscularis mucosae


Dense connective tissue. Includes: blood and lymphatic vessels, lymphoid follicles, and submuscosal nerve plexus


submucosa


Responsible for segmentation and peristalsis. Includes inner circular and outer longitudinal layers, myenteric nerve plexus and sphincters in some regions.


muscularis externa


Replaces by the fibrous adventitia in the esophagus. Retropertitoneal organs have both an adventitia and serosa.


visceral peritoneum


Bounded by lips, cheeks, palate, and tongue. Oral orifice is the anterior opening. Lined with stratified squamous epithelium.


oral (buccal) cavity


Contains orbicularis oris, and buccinator muscles, vestibule, labial frenulum and oral cavity proper lies within the teeth and gums.


lips and cheeks


Recess internal to lips and cheeks, external to teeth and gums.


vestibule


Median attachment of each lip to the gum.


labial frenulum


Two types of palates:


hard palatesoft palate


Palatine boes and palatine procces of the maxillae; slightly corrugated to help create friction against the tongue.


hard palate


Fold formed mostly of skeletal muscle; closes off the nasopharynx during swallowing and uvula projects downward from its free edge


soft palate


Three functions of the tongue:


repositioning and mixing food during chewingformation of the bolusinitiation of swallong, speech, and taste


Part of tongue that attaches to the floor of the mouth.


lingual frenulum


Three types of salivary glands:


extrinsicintrinsic (buccal)secretion (saliva)


Glands found in parotid, submandibular, and sublingual.


extrinsic salivary glands


Glands that are scattered in the oral mucosa.


intrinsic (buccal) glands


Four fucntions of secretion (saliva):


cleanses the mouthmoistens and dissolves food chemicalsaids in bolus formationcontains enzymes that begin the breakdown of starch


Primary and permanent dentitions are formed by age ___.


21


Two sets of teeth:


deciduouspermanent


Erupts at 6-24 months of age (20 of them); and roots are resorbed, teeth fall out at 6-12 years as permanent teeth develop.


deciduous teeth


All except third molars erupt by the end of adolescence (32 of them)


permanent


Chisel shpaed for cutting.


incisors


Fanglike teeth that tear or pierce.


canines


Have broad crowns with rounded cusps for grinding or crushing


premolars (bicuspids)molars


The exposed part above the gingiva (gum).


crown


The crown is covered by _____ which is the hardest substance in the body (calcium salts and hydroxyapatite crystals)


enamel


Portion embedded in the jawbone; connected to crown and neck.


root


Calcified connective tissue; covers root and attaches it to the periodontal.


cementum


Forms fibrious joint called a gomphosis.


periodontal ligament


Groove where gingiva borders the tooth.


gingival sulcus


Bonelike material under enamel; maintained by odontoblasts of pulp cavity.


dentin


Cavity surrounded by dentin.


pulp cavity


Connective tissue, blood vessels, and nerves.


pulp


Extends from pulp cavity to the apical foramen of the root.


root canal


Allows passage of food, fluids, and air; stratified squamous epithelium lining; made up skeletal muscle layers.


oropharynx and laryngopharynx


Inner longitudinal, outer pharyngeal constrictors.


skeletal muscle layers of pharynx


Flat muscular tube from laryngopharynx to the diaphragm to the gastroesophageal sphincter in the superior aspect of the stomach; approximately 25cm long; has adventitia instead of serosa.


esophagus (gullet)


Four digestive processes of the mouth:


ingestionmechanical digsestionchemical digestionpropulsion


Mastication is partly voluntary, partly reflexive.


mechanical digestion


Contains salivary amylase and lingual lipase.


chemical digestion


Deglutition (swallowing).


Propulsion


The parts of the stomach's gross anatomy:


cardiac region (cardia)fundusbodypyloric regionlesser/greater curvationleser/greater omentum


Surrounds the cardiac orifice.


cardiac region


Dome-shaped region beneath the diaphragm.


Fundus


Midportion of stomach.


body


Antrum, pyloric canal, and pylorus; pylorus is continuous with the duodenum thorugh the pyloric valve (sphincter).


pyloric region


Convex lateral surface.


greater curvature


Concave medial surface.


lesser curvature


From the liver to the lesser curvature.


greater omentum


Drapes from greater curvature; anterior to the small intestine


greater omentum


Three factors of stomach anatomy:


four tunicsmuscularis and mucosa are modifiedmucosa


Three layers of smooth muscle; inner oblique layer allows stomach to churn, mix, move, and physically break down food.


muscularis externa


Simple columnar epithelium composed of mucous cells; layer of mucus traps bicarbonate-rich fluid beneath it; gastric pits lead into gastric glands


mucosa


Four cell types of gastric glands:


mucous neck cells (secrete thin, acidic mucusparietal cells - HCLchief cells - pepsinogenenteroendocrine cells


Major organ of digestion and absorption; 2-4m long; from pyloric sphincter to ileocecal valve; has subdivision.


small intestine


Subdivision of small intestines:


duedenum (retroperitoneal)jejunum (attached posteriorly by mesentery)ileum (attached posteriorly by mesentery)


The bile duct and main pancreatic duct. Joined at the hepatopancreatic ampulla, enters the duodenum at the major duodenal papilla and are controlled by the hepatopancreatic sphincter.


Duodenum


What three factors increases surface area of proximal part for nutrient absorption?


circular folds (plicae circulares)villimicrovilli


Motile fingerlike extension (~1mm high) of the mucosa. Includes villus epithelium; simple columnar absorptive cells (enterocytes) and globelet cells.


villi


Projections (brush border) of absorptive cells; bear brush border enzymes.


microvilli


Secretory cells that produce intestinal juice; enteroendocrine cells; intraepithelial lymphocytes (IELs); paneth cells; stem cells


intestinal crypt epithelium


Release cytokines that kill infected cells


intraepithelial lymphocytes (IELs)


Secretes antimicrobial agents (defensis and lysozyme).


paneth cells


Peyer's patches protect distal part against bacteria; duodenal (Brunner's) glands of the duodenum secrete alkaline mucus.


submusoca


Largest gland in the body; four lobes - right, left, caudate,a nd quadrate.


liver


Separates the (larger) right and (smaller) left lobes; suspends liver from the diaphragm and anterior abdominal wall.


falciform ligament of liver


Remnant of fetal umbilical vein along free edge of falciform ligament.


round ligament (ligamentum teres) of liver


Three types of ssociated structures of liver:


lesser omentum anchors liver to stomachhepatic artery and vein at the porta hepatisbile ducts


Common hepatic duct leaves the liver; cystic duct connects to gallbladder; formed by the union of the above two ducts.


bile ducts


Two factors of liver lobules:


hexagonal structural and functional unitslongitudinal central vein


Filter and process nutrient-rich blood; composed of plates of hepatocytes (liver cells).


hexagonal structural and functional units of liver lobules


Bile duct receives bile from bile canaliculi; portal arteriole is a branch of the hepatic artery; hepatic venule is a branch of the hepatic portal vein.


portal triad at each corner of lobule


Leaky capillaries between hepatic plates


liver sinusoids


(hepatic macrophages) in liver sinusoids.


Kupffer cells


Four functions of hepatocytes:


process bloodborne nutrientsstore fat-soluble vitaminsperform detoxificationproduce ~900ml bile per day


Yellow-gree, alkaline solution containing bile salts, bilirubin, cholesterol, neutral fats, phopholipids and electrolytes.


bile


Cholesterol derivatives that function in fat emulsification and absorption.


bile salts


Pigment formed from heme.


bilirubin


Thin-walled muscular sac on the ventral surface of liver; stores and concentrates bile by absorbing its water ions; releases bile via the cystic duct, which flows into the bile duct.


gallbladder