Chap 17 Study Guide

What is hemostasis? What are the three phases of hemostasis?

Fast series of reactions for stoppage of blood
Vascular Spasm Platelet plug formation
Coagulation

What is vascular spasm?

Vasoconstriction of damaged blood vessel

Conversion of prothrombin into the enzyme thrombin requires?

Prothrombin Activator

Which sequence is correct for the following events?
prothrombin ? thrombin fibrinogen ? fibrin
clot retraction formation of thromboplastin

2,3,4,1

What is fibrinolysis?

Dissolving of clots

What enzyme can digest fibrin and dissolve a clot?

Plasmin

What is coagulation?

A set of reactions where blood is turned from a liquid to a
gel.

What conditions impair coagulation?

Vitamin K deficiency Severe Hypocalcemia
Liver disease

What are thromboembolic disorders? What are thrombus and embolus?

Thrombocytopenia: Undesirable Dot formation. Thrombus:
Clot that develops and persists in an unbroken blood vessel, Many
lead to tissue death Embolus: A thrombus freely floating in
the blood stream, Can cause strokes

Learn the examples of the bleeding disorders covered in this chapter.

Thrombocytopenia: Deficient number of circulating proteins
(Platelets? < 50,000 mm3) Impaired liver
function: Inability to synthesize procoagulants can also prevent the
liver from producing bile, Impairing fat and Vitamin K
absorption Hemopilias: Include Vitamin K, Hepatitis,
cirrhosis; Deficiency of procoagulants ( Factor VIII, IX, XI)