H2O is ___% of total body weight
60%
___ of H2O is found in the ___ and __ in the ECF
2/3 found on ICF and 1/3 in the ECF
The main extracellular fluid (ECF) are found in the:
Interstitial Fluid and ____ ____ these are the main ones but it
also consist of other minor Extracellular body fluids like ___ and Lymph
Blood Plasma, CSF
The intracellular fluid (ICF) fluid within our cells is found in the
cells of the body called ___ _____
The Cytosol
What are the principal ions in the ECF?
Na+ ( the main ion)
Cl-
and HCO3 (Bicarbonate)
What are the principal ions in the ICF?
K+ ( the main cation)
Mg+
and PO4 (phosphate ions)
plus negatively charged Proteins
Composition of body fluids respond to changes in the ___ NOT in the ___
ECF, ICF
Water moves back and fourth freely within the ___ Compartment
ECF
When water is lost, but electrolytes are retained, _____ moves water
from the ___ into the ___ until balance is restored
Osmosis, ICF, ECF
What are the two important effects ADH has when the increase is released?
1) it stimulates water conservation by the kidneys, reducing urinary
water losses (therefore a person exposed to days with no water they
will have high ADH levels)
2) Stimulates the Thirst center, promoting the intake of fluids
The higher the ______ concentration of aldosterone, the more
efficiently the kidneys conserve or retain __+
Plasma, Na+
Aldosterone is ______ in response to rising __+
Secreted, K+
Dehydration is associated with�
1)____
2)____
3)____
1) Severe Thirst
2) Fall in plasma volume
3) Blood Pressure
Rate of ______ uptake across the digestive tract is directly
proportional to ____ ____
Sodium, Dietary intake
If large amounts of salt are consumed(like a meal high in salt) the
plasma ___+ concentrations will rise temporarily. Therefore, resulting
in a temporary increase in ____ ______
Na+, blood volume
Aldosterone levels:
Aldosterone regulates the amount of ______ secreted by the _____
it also promotes the _____ retention in the kidneys
Potassium, kidney, Sodium
When Aldosterone increases __+ ____ as well as K+ _____, this excess
of potassium is ______ from the body by the _____
Na+ Reabsorbs,secretion, eliminated, Kidneys
Calcium Balance:
Calcium homeostasis primarily reflects an interplay between the
reserves in the ____, the rate of ______ across the digestive tract,
and the rate of ______ at the kidneys
bones, absorption, excretion
pH Control:
The pH of the ECF remains between ____ and ____
7.35 and 7.45
If Plasma levels fall below 7.35 (academia), ______ results
Acidosis
If plasma levels rise above 7.45 (Alkalemia), ______ results
Alkalosis
The ____is the most important factor affecting the __ in body tissues
PCO2, pH
When the pH of body fluids beings to fall (more acidic) ____ will
bind a ______ ion at the ____ portion (-NH2)
Proteins, Hydrogen, Amino
The primary role of The Carbonic Acid (CO2) - Bicarbonate Buffer
System is to prevent __ changes caused by ____ ____ and fixed acids in
the ___
pH, Organic acids, ECF
Increasing or decreasing the the rate of _________ alters the __ by
lowering or raising the ____
Respiration, pH, PCO2
When the PCO2 rises, the __ ____
(Making it more Acidic)
pH falls
When the ____ ____, pH rises
(More Alkaline)
PCO2 falls
What is the usual cause of Respiratory Acidosis?
Hypoventilation (abnormal low respiratory rate)
Respiratory Acidosis;
The pH will be _____ because of the cause of ______
Lower, because of hypoventilation
Respiratory Acidosis;
Chronic Respiratory Acidosis develops when normal respiratory
function has been compromised
Examples of conditions fostering Chronic Respiratory acidosis include?..
Emphysema, Congestive Heart Failure, and Pneumonia
Problems with Respiratory Alkalosis are rare, but they primarily involve?
lose of
Consciousness(for ex because of high altitude)
Patients on mechanical Respirators
and individuals with brain stem injuries
What are the 3 major causes of Metabolic Acidosis?
1) Production of Fixed Acids OR Organic Acids
2) Impaired ability to excrete at the Kidneys (person suffering
with inflammation of the kidneys will show these symptoms)
3) Severe Bicarbonate Loss, Chronic Diarrhea
A person suffering from chronic diabetes will exhibit signs of ____ ____
Metabolic Acidosis
What is an example of Metabolic Alkalosis?
also a person consuming large amounts of antacids to settle an upset
stomach are at risk of of developing _____ _____
A person with prolong Vomiting
Metabolic Alkalosis