Who came up with the Milieu Interieur" phrase
Claude Bernard the first experimental physiology the Milieu Interieur is meant to describe the internal environment or HOMEOSTASIS
What does Homeostasis mean from greek meaning
Internal environment
What percentage of the body is water weight and the volume of blood
60% of the body is water weight42 liters
What is the volume of the ICF or the Intracellular Fluid
2/3 of the total body fluid
What is the volume of ECF or Extra-Cellular- membrane
1/3 of the total body weight
The ECF entails what other fluid bodies which make it up
The ECF includes the interstitial fluid (between cells), Lymph-node, Plasma and/or Serum
ECF is in a continual statics state True or Flase
False it is always in a constant motion
Why is the ECF dynamic
So that is it can remove waste and other metabolites.
What is the route that ECF takes
Through the blood, capillaries, interstitial space,
How far are cells away from the capillaries
50µm
What parameters does the ECF control and example
Gases O₂ and CO₂Temp 37°pH 7.40Nutrients glucose, amino acids, lipids(Fatty Acids)Wastes CO₂, UreaElectrolytes Na⁺, Ca²⁺, K⁺, Cl⁻
What is negative feedback
The change in the initial response in the opposite direction ExChanges in BP
What is positive Feedback
A change in the initial response in the same directionExBlood clotting
How is BP regulated through feedback
The aorta and the carotid artery have a sensor called the "Baroreceptor" located in the Medulla
How does it feedback for low blood pressure
It increases BPPeripheral vasoconstriction Strengthen heart contraction Stimulation of Epinephrine (Come from the adrenal glands)Increase heart rate
How does it feedback for high blood pressure
Decreases BPPeripheral vasodilationDecrease HRDecrease contraction strength
What is an example of positive feedback
Child birth Oxytocin stimulates contractions and child birth
How does Oxygen and release work for hemoglobin
The RBC picks up the oxygen from the lungs, the oxygen if then ONLY released to the tissues that are low in oxygen.
What does the pancreas do to carbohydrate metabolism
The pancreas controls carbohydrate levels thus controlling glucose