Chapter 5 Pharmacodynamics

pharmacodynamics

how a medicine changes the body

frequency distribution curve

a graphical representation of the number of patients responding to a drug action at different doses

median effective dose

the dose required to produce a specific therapeutic response in 50% of a group of patients (ED50); sometimes reported as the average or standard dose

potency

concept reflecting a drug that will produce a therapeutic effect at a lower dose

efficacy

the magnitude of maximal response that can be produced from a particular drug

agonist

a drug that produces the same type of response as the endogenous substance