WBC Disorders CD Markers/TLocs

ALL

B-ALL: CD10, 19+
T-ALL: CD1, 2, 5, 7+
TdT+

Burkitt lymphoma

CD10, 19, 20+
t(8:14), t(2:8), t(8:22)
Decr Bcl-2

CLL/SLL

CD5, 19, 20, 23+

Follicular lymphoma

CD10, 19, 20+
CD5-
t(14:18), Bcl-2+

DLBL

CD10, 19, 20+
TdT-

HL: nodular sclerosis

CD15, 30+

HL: mixed cellularity

CD15, 30+

HL: lymphocyte rich

CD15, 30+

HL: lymphocyte depletion

CD15, 30+

HL: lymphocyte predominant

CD15, CD30-

Multiple myeloma

CD38, 138+

Mantle cell lymphoma

CD5, 19, 20+
CD23-
Cyclin D1 over expression t(11:14)

Hairy cell leukemia

CD11c, 19, 20, 25, 103+

Adult T cell leukemia/lymphoma

CD2, 3, 5+
Tax activates NF-KB

Mycosis fungoides

CD2, 3, 5+

Langherans histiocytosis

S100, CD1a

Acute myelogenous leukemia

PML-RAR ? gene t(15:17)

Chronic myelogenous leukemia

Philadelphia c'some Bcr-Abl gene t(9:22)