Bleed 1 vs Bleed 2

1

Bleed two has a bigger ab titer than bleed one because there is an extra ag-ab complex that isn't present in the first bleed.

2

One possible reason is that the ab titer in bleed one was too low and didn't reach the equivalence point with the antigen.

3

In bleed 1 there are a maximum of three ab-ag complexes. In bleed 2 there are four.

4

The antigen concentration decreased clockwise, since the antigens are diffusing radially from the point of application.

5

The bigger the diameter the lower the antigen concentration

6

If you look at circle "C" in bleed one when the dilution was 1/2 the antigen had to diffuse further away from the well.