Lab Practical (Fill-Ins)

Most sensitive method for measuring low molecular antigens such as IL-2.

Sandwich ELISA

Cells can be tagged with fluorescent monoclonal antibodies for separation by this method.

FACS

Two different enzymes conjugated to the secondary antibody in ELISAs

Alkaline Phosphatase and Peroxidase

Cell size in flow cytometry is measured by this.

Forward Light Scatter

The number of wells in a typical Ouchterlony plate?

7

This method can detect different epitopes on the same antigen.

Ouchterlony

Which method of measuring antibody titers is most sensitive.

ELISA

Antigens can be coated onto red blood cells in this type of assay

Agglutination

3 blockers used in ELISA

BSA, Milk & Tween 20

The matrix used for electrophoresis in western blot

acrylamide

Antibody may be incorporated directly into agarose in which 2 methods?

Mancini & oudin

Avidin binds to this

Biotin

Maximum precipitation occurs at this point where the concentrations of Ab and Ag are optimal

Equivalence

If too much antibody is present for precipitation it is called?

Zone of antibody excess

Best method for antigen separation?

Western Blot

Agent added to samples to allow protein separation only by molecular weight in Western Blots.

SDS

How are antigens transferred from gel to membrane in Western Blots?

Electrophoresis

Two methods involving antigen separation prior to contact with antibody?

Immunoelectrophoresis and Western Blot

PAGE is called reduced when this agent is added to samples.

mercaptoethanol